A motorcyclist has been rushed to hospital with life-threatening injuries after being struck on the Gardiner Expressway, paramedics say.
It happened in the eastbound lanes of the highway west of the Don Valley Parkway at around 10:30 p.m.
The circumstances surrounding the incident were not immediately clear.
A second person travelling on the motorcycle was transported to hospital with serious injuries, paramedics said.
The ages and genders of the patients were not immediately provided.
The eastbound lanes have been closed at Jarvis Street as police investigate.